Virtual Tour
VIRTURAL TOUR
KOA ISEI Zao Factory
― Virtual Tour ―
KOA ISEI Zao Factory enable us to manufacture highly pharmacologically active injectable drugs that require advanced technologies. Please take a look inside the factory, which is usually closed to the public to keep sterile conditions.
VIRTURAL TOUR
KOA SHOJI Pharmaceutical Analysis Center ensures Safety, Security and Stable Supply
KOA SHOJI has their own "Pharmaceutical Analysis Center" with the most advanced analytical equipment. In addition to providing a stable supply of existing products, they also make proposals for new products and provide support from the R&D stage.
Specifically, they research the marketability, draft specifications and concepts, and select new sales items.
Please find 3 equipment to check quality information and select API suppliers.
- Color-difference Meter SE 6000（Nippon Denshoku）
- Desktop Scanning Electron Microscope
- X-Ray Diffractometer
Color-difference Meter SE 6000
（Nippon Denshoku）
Color-difference Meter SE 6000（Nippon Denshoku）
A color-difference meter measures solids, liquids, and powders. The appearance test is one of the test for pharmaceutical raw materials and is evaluated visually. Different people see colors differently, which can cause problems, especially with overseas suppliers. By using this equipment, we can show the differences in color in the data and can solve the troubles.
All these pictures are of the same substance, but the colors may vary depending on the supplier.
Such color differences can be clearly observed in the data using a colorimeter.
Desktop Scanning Electron Microscope
Desktop Scanning Electron Microscope
The electron microscopes can magnify more than optical microscopes. It can also distinguish slight differences in the shape of the crystals that cannot be observed with an optical microscope. It also can identify the substances.
Differences in crystals as seen by the electron microscope.
X-Ray Diffractometer(Rigaku)
X-Ray Diffractometer
The differences in the crystals can be clearly read as data using an X-ray diffractometer.
Crystal structure is one of the most important factors in designing pharmaceutical formulations because it affects solubility and dissolution speed. At KOA SHOJI Pharmaceutical Analysis Center, we have four X-ray diffractometers to check the crystal structure.
More advanced analysis is possible using a combination of several instruments.
Differences in crystals as seen by X-ray diffractometer
Granular crystals
Mixture
Needle-like crystals
